Drug and alcohol commissions were established statewide by act 301 of the South Carolina legislature in 1972. The purpose of the commissions was to plan for and administer state and federal funds allocated for the treatment and prevention of substance use and dependence.

In 1985 the Horry County Council passed County Ordinance 6-85 formally establishing the Horry County Commission on Alcohol and Drug Abuse (HCCADA) and designating it as the single county authority for alcohol and drug abuse programming. In the spring of 2000, the HCCADA became Shoreline Behavioral Health Services.